The Las Vegas Raiders and Los Angeles Chargers meet in Week 13 of the 2025 NFL season trending in opposite directions. The Raiders have not clicked under first-year head coach Pete Carroll, and the move to bring in quarterback Geno Smith has not worked out. The Chargers had a bye in Week 12 but have won four of their last six games and bring a 7-4 record into the game. Los Angeles won the first meeting between these teams in Week 2, 20-9.
Kickoff from SoFi Stadium in Los Angeles is set for 4:25 p.m. ET on CBS and Paramount+. The Chargers are 10-point favorites in the latest Raiders vs. Chargers consensus odds, and the total comes in at 40.5 after opening at 42.5. The Chargers are -571 money line favorites (risk $571 to win $100), while the Raiders are +414 underdogs. New Paramount+ users can get a one-week free trial when signing up, and they can catch all the Week 13 NFL action on the service. Sign up for Paramount+ here.
Los Angeles has been elite at home defensively but struggles mightily on the road. The Chargers are 2-2-1 ATS as home favorites and 2-3 to the Over at home, while the Raiders are 3-5 ATS as underdogs and are 1-4 to the Over as the road squad.
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Final odds: +525 at DraftKings (wager $100 to win $525)
The Chargers dominated the Raiders in Week 2, particularly defensively, and the SportsLine Projection Model sees a similar situation playing out here. The Chargers cover as 9.5-point favorites in 52% of simulations but the Raiders offer more value on the money line as +411 underdogs, winning in 25% of simulations. The Over on 40.5 hits in 64% of simulations.
Raiders vs. Chargers score prediction: Chargers 28, Raiders 18